Who makes sorafenib? Sorafenib was co-developed as well as co-marketed by Bayer and Onyx Pharmaceuticals as Nexavar. Sorafenib uses: It is basically a kinase inhibitor class of drug recommended in the treatment of primary Kidney cancer, FLT3-ITD positive AML, radioactive iodine resistant advanced thyroid carcinoma, advanced primary liver cancer and advanced renal cell carcinoma. What are the signs of kidney cancer? Kidney cancer generally called renal cancer occurs in Kidneys and slowly spreads to other body parts. At the initial phase, no signs of Kidney cancer has been detected however at advancing stage the common signs and symptoms of Kidney cancer include weight loss, loss of appetite, blood in urine, lower back pain, anemia, fever, tiredness, the formation of lump on lower side back Something about liver and thyroid cancer Liver cancer: Cancer that begins in the cell of the liver is known as liver cancer. The most common type of cancer is hepatocellular carcinoma. Other types include neuroblastoma, intrahepatic cholangiocarcinoma. Some common symptoms of liver cancer include nausea, vomiting, loss of appetite, abdominal swelling, white stool, jaundice, weight loss, weakness, and fatigue. Thyroid cancer: Cancer in the thyroid gland of the human body that produces hormones responsible for maintaining blood pressure, regulating heart rate, body temperature, and weight. Several types of thyroid cancer exist in which some are slow-growing whereas some are aggressively growing. At the initial stage, there is typically no signs and symptoms of Thyroid cancer however with the advancement of Cancer some symptoms such as a lump in the neck, difficulty in swallowing, swollen lymph node in the neck, changes in the voice, pain in the neck and throat occurs Is sorafenib considered chemotherapy? It is a targeted therapy drug that works by stopping or slowing down the multiplication and growth of cancerous cells. Sorafenib can cure liver cancer if used as a first-line treatment before surgery. How does sorafenib work? Targeted therapy works by identifying the specific functioning of cancerous cells and finding its way to inhibit or block the protein synthesis, cell division, or cell growth. Sorafenib blocks cancerous cell growth in different ways. This drug targets the production of several enzymes in the cell or on the surface of the cancerous cell. These targeted enzymes are involved in angiogenesis. This therapy works as an antiangiogenesis that blocks the supply of oxygen to the tumor so that they starve to death. Sorafenib dose: Sorafenib is available in a tablet form of 200 mg concentration. Two tablets of 200mg (400mg dose) are taken daily according to the doctor's prescription. How to take sorafenib tablets: Sorafenib 200mg is consumed orally without food. The pill should be taken either before a meal or after 2 hours of a meal. Swallow the tablet as a whole. Do not crush, grind, or smash the tablet. Sorafenib side effects: The common side effect of sorafenib are mentioned below: ● Diarrhea ● Abdominal pain ● Rash ● Nausea ● Hand-foot syndrome ● Fatigue ● Weight loss ● Redness, swelling, and peeling of skin in hands and feet. ● Gastrointestinal pain ● Infection ● Hypertension ● Hemorrhage Some serious adverse reaction of sorafenib tablets are discussed below: ● Cardiovascular disorder ● Hypertension ● Bleeding ● Gastrointestinal perforation ● Embryo-fetus damage ● Drug-induced liver injury ● Dermatological toxicity Note: For full information patients must talk about prescribing information with their healthcare provider. Tollfree - +91 1800 889 1064 International Pharmaceutical Wholesalers Read - KIDNEY CANCER INTRODUCTION A VISUAL GUIDE TO BREAST CANCER
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