Eltrombopag is approved in order to treat adult patients with:
Chronic ITP: Initiate eltrombopag at 50mg once in a day for most adult and pediatric patients aged 6 years and older, and at 25mg once in a day for pediatric patients aged 1 to 5 years. Dose reductions are required for patients with hepatic impairment and some patients of Asian ancestry. Adjust to maintain the platelet count more than or equal to 50 x 109/L. It is not recommended to exceed eltrombopag 75 mg per day. Chronic Hepatitis C-associated Thrombocytopenia: Initiate eltrombopag at 25 mg once in a day for all patients. Adjust to achieve the target platelet count needed in order to initiate the antiviral therapy. It is not recommended to exceed a daily dose of eltrombopag 100 mg. First-line Severe Aplastic Anemia: Initiate eltrombopag for aplastic anemia once in a day at 2.5 mg/kg (in pediatric patients aged 2-5 years old), 75 mg (pediatric patients aged 6-11 years old), or 150 mg for patients aged 12 years and older concurrently with the standard IST immunosuppressive therapy. Refractory Severe Aplastic Anemia: Initiate at eltrombopag 50 mg once in a day. Reduce the initial dose in those patients who are with hepatic impairment or patients of Asian ancestry. Adjust to maintain the platelet count more than 50 x 109/L. It is not recommended to exceed the eltrombopag 150mg per day. Side Effects: In adult patients with ITP, the most common side effects are:
In pediatric patients age 1 year and older with ITP, the most common side effects are:
In patients with chronic hepatitis C-associated thrombocytopenia, the most common side effects are:
Drug Availability: Supplied as eltrombopag 12.5 mg, eltrombopag 25 mg, eltrombopag 50 mg, and eltrombopag 75 mg tablets, and is available as an oral suspension in 12.5 mg and 25 mg packets of powder for reconstitution. Storage: Store eltrombopag tablets at room temperature between 68°F-77°F (20°C-25°C). Keep eltrombopag in the bottle given to you. Store eltrombopag for oral suspension at room temperature between 68°F-77°F (20°C -25°C). After mixing, eltrombopag should be taken right away but may be stored for no more than 30 minutes between 68°F-77°F (20°C-25°C). Throw away (discard) the mixture in case it is not used within 30 minutes. FAQ's What is eltrombopag Olamine? Eltrombopag Olamine specifically is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis stimulating activity. Is Eltrombopag an immunosuppressant? Eltrombopag, a thrombopoietin-receptor agonist, is added to the standard immunosuppressive therapy for patients with the previously untreated severe aplastic anemia. What is thrombocytopenia? Thrombocytopenia mainly is a medical term that means the blood does not contain the enough platelets, which are crucial for blood clotting. Several patients with the infection of hepatitis C have this condition, which may mean they are not able to take some of the drugs they need in order to treat hepatitis C, such as interferon. Is ITP a serious disease? In major cases, the condition ITP isn't serious or life-threatening. Acute ITP in children often resolves within 6 months or less. Chronic ITP may last for several years. Individuals can live for decades with this condition, even those with the severe cases.
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Canmab (salt name trastuzumab) is prescribed for the treatment of metastatic breast cancer patients who have HER2 overexpressing tumours. The canmab injection is prescribed for the treatment of adult patients with HER2+ve early breast cancer. Canmab together with capecitabine or 5-fluorouracil and cisplatin is prescribed for the treatment of adult patients with HER2+ve metastatic adenocarcinoma of the stomach or gastroesophageal junction who have not given prior anti-cancer treatment for metastatic disease. How it is given: The trastuzumab injection is recommended to be given by slow injection into a vein and injection just under the skin by a healthcare practitioner. Very Common Side Effects: Very commonly reported canmab side effects may include:
Precautions:
How to store Canmab: Keep Canmab out of the sight and reach of the infants/children. Store this drug in a refrigerator (2°C to 8°C). Keep the Canmab vial in the outer carton in order to protect from the light. Avoid freezing Canmab. Upon opening of the vial, solution needs to be used immediately. Price of Trastuzumab: The trastuzumab injection price may vary from generic to branded drugs. The canmab 440 mg price for a vial of 1mL injection is around 59900 INR. NOTE: The piece of information provided about canmab 440 mg injection in this article is just for informational purposes and is not served as a substitute for the medical treatment, consultation, diagnosis of a qualified healthcare practitioner. FAQ's What is trastuzumab injection? Trastuzumab 440 mg falls under the class of drugs named monoclonal antibodies. It acts in order to stop the growth of the cancer cells. What is trastuzumab used for? Canmab is the generic brand of a medicine named trastuzumab. Treatment of breast cancer, oesophageal cancer and stomach cancer are the trastuzumab injection uses. Is trastuzumab a chemotherapy drug? Trastuzumab specifically is a targeted cancer medication and can also be addressed by its brand name, Herceptin. What are the side effects of Herceptin? The most commonly occurring side effects of herceptin (innovator brand name) are headache, diarrhea, nausea, chills, fever, heart problems, infection and insomnia. Is trastuzumab effective for breast cancer? Trastuzumab following chemotherapy is effective in the treatment of HER2+ve breast cancer. Trastuzumab therapy for 1 year after standard chemo improved disease-free survival in female patients with HER2+ve early breast cancer. How much does trastuzumab cost? The trastuzumab price may vary from branded to non-branded drugs. The canmab 440 mg price for a vial of 1mL injection is around 59900 INR. Humira is prescribed for reducing the signs and symptoms and inducing as well as maintaining the clinical remission in patients who are with moderately to severely active Crohn's disease who have had an inadequate response to the conventional therapy. Humira is used in order to reduce the symptoms and induce the clinical remission in these patients in case they have also lost response to or are not tolerant to infliximab. Dosage: The recommended dose of humira for the treatment for crohn's disease is 160 mg initially on Day 1 (given as 4 adalimumab 40 mg injections in one day or as two 40 mg injections per day for 2 consecutive days), followed by 80 mg two weeks later (Day 15). Two weeks later (Day 29) begin a maintenance dose of adalimumab 40 mg every other week. Aminosalicylates or corticosteroids can be continued while on treatment with this drug. Azathioprine, 6-mercaptopurine (6-MP) or MTX may be continued during humira injection uses, if necessary. Use of this drug in Crohn's disease beyond 1 year has not been evaluated in the controlled clinical studies. What are the side effects of Humira? The common side effects of humira include:
Adalimumab (humira) specifically is a man-made antibody, made from the living cells, so it’s known as a biological drug. The adalimumab 0.5 mg targets a protein in the body named TNF-alpha, which is naturally produced by the body. It plays a crucial role in order to help your immune system fight against infections. But excess TNF-alpha may damage the cells lining the gut. This is thought to partly cause the gut inflammation of patients with Crohn’s disease. This medication binds to TNF-alpha, resisting its harmful effects as well as reducing inflammation. This helps in order to relieve the symptoms. Adalimumab can also be addressed as an anti-TNF medicine. How much does humira cost? The humira injection cost may vary from branded to non-branded drugs. Prices may range from around 16,000 INR to 25,000 INR. Storage Guidelines: Humira needs to be refrigerated at 2° to 8° C (36° to 46° F). Avoid freezing it. It is not recommended to be used if frozen even in case it has been thawed. While traveling, Humira needs to be placed/stored in the cool carrier with an ice pack. Prefilled syringes should be protected from exposure to the light. Store humira pen 40 mg in the original carton until the time of administration. What are some other common Crohn's disease medications: Some common crohn's disease medications are listed as:
NOTE: The information provided in this article is only for informational purposes and is not served as a substitute for the medical treatment, consultation, diagnosis, of a qualified healthcare practitioner. What is thiotepa used for?
Thiotepa (TEPADINA) is a chemotherapy drug used to treat brain tumor, breast cancer, non-small cell lung cancer and ovarian cancer. It is prescribed together with other cancer medication while hematopoietic progenitor cell transplantation (HPCT). How does thiotepa act? Thiotepa is an anti-cancer medication. It acts in order to damage the genetic material (DNA & RNA) of the cancerous cells. This helps in stopping their growth as well as multiplication. How is this drug best taken? The thiotepa 15 mg injection should be used as ordered by your healthcare practitioner. Read all information given to you. Follow all instructions closely. The thiotepa dose is given as an infusion into a vein over a period of time. It can be administered into the belly or chest cavity as a wash. It can be administered a catheter into the bladder. If you're taking this medication on the skin, wash it off immediately with soap as well as water. What are possible side effects of thiotepa? All drugs may cause side effects. Although, several people have no adverse events or any minor adverse events. Call your doctor or get medical assistance if any of thiotepa side effects or any other side effects bother you or is persistent: Hair loss Feeling tired, or weak Headache Stomach pain Diarrhea Throwing up Upset stomach Feeling less hungry Irritation where the drug is given If these adverse reactions happen, discuss with your healthcare provider about ways to decrease these adverse reactions. Report your healthcare practitioner immediately in case any of these reactions bother you. What do I need to inform my doctor prior to taking thiotepa?
What are other things I need to do while on thiotepa?
What should I do if I miss/forget a dose? Contact your healthcare practitioner in order to find out what to do. How do I store or throw out thiotepa? If you're storing thiotepa at home, discuss with your healthcare practitioner about how to store thiotepa. How much does thiotepa cost? Vial of 1 powder for injection of thiotepa is around 17,452 INR. The thiotepa price may vary from branded to non-branded (generic) drugs. Note: Before starting thiotepa treatment, consult a physician. To know more about thiotepa, read full prescribing information. Read - Medicine for Breast Cancer Treatment What is Midostaurin used for? Midostaurin (Rydapt), specifically is a multi-targeted protein kinase inhibitor, investigated in order to treat acute myeloid leukemia that is FLT3-positive (AML), Mast Cell Leukemia (MCL), advanced systemic mastocytosis (ASM) and systemic mastocytosis with an associated hematological neoplasm (SM-AHN). Recommended dose for patients with AML: On days 8 - 21 of each cycle, consume 50 mg (2 capsules) twice daily. This means you have to take 4 capsules per day. The healthcare provider will determine how long each cycle will last. Recommended dose for Patients with ASM, SM-AHN, or MCL: Consume 100 mg (4 capsules) twice daily. This means you have to consume 8 capsules per day. How to take Midostaurin? It should only be started by a physician experienced in anti-cancer drugs. Consume it exactly as your healthcare provider has instructed you. Take midostaurin by mouth with the whole glass of water. Do not open, crush or chew. Consume this medication twice daily at about 12 hour intervals. For instance, consume it at breakfast and dinner time with food in order to help prevent nausea. How does midostaurin work? It is believed that the midostaurin blocks the action of some enzymes (kinases) of cells that are abnormal. This blocks their division as well as growth. Side Effects: The most commonly reported midostaurin side effects include:
Is Midostaurin a chemo drug? Midostaurin mainly is a targeted therapy called a kinase inhibitor. It acts by blocking the several proteins (kinases) on cancer cells, including FLT3, that may help the cells grow. Overdose: If you think you have consumed too much Midostaurin, or if someone else accidentally consumes your medicine, contact your healthcare professional as soon as possible. Missed Dose: In case of missed dose, skip the missed dose and continue as usual. Avoid taking a double dose in order to make up for the forgotten capsules. Instead, wait until it is time for your upcoming dose. If you pukes, must not consume an additional dose of midostaurin capsules 25 mg, but should consume the next usual prescribed dose. What is the price of Rydapt? It is a member of the multikinase inhibitors drug. As with all medicines, the rydapt 25mg price can vary, depending upon the company/pharmacy. You can Buy Rydapt (midostaurin) online very easily. Where do I get Rydapt at the best price? The midostaurin 25 mg capsules cost in india is absolutely reasonable. In order to get Rydapt at the best price you need to choose a WHO-GDP & ISO certified pharmaceutical wholesaler company. Read - Let's Talk About Midostaurin Chronic myeloid leukemia also can be addressed as CML. It is specifically a kind of clonal myeloproliferative disorder driven by the oncogenic tyrosine kinase BCR-ABL. The discovery of the TKI (tyrosine kinase inhibitor) imatinib revolutionized for managing patients with the Chronic Myeloid Leukemia. However, imatinib may have a significant adverse reactions, and is not much effective in all the patients. With the development of the second-generation (dasatinib and nilotinib) as well as third-generation (ponatinib) TKIs (tyrosine kinase inhibitors) sought to address the issue of the imatinib-resistance and -intolerance and furthermore, in order to determine if all these agents are quite superior to the imatinib. Dasatinib, mainly a multitargeted inhibitor, is quite effective and useful against the most BCR-ABL kinase domain mutations resistant to the imatinib and able to induce deeper and rapidly molecular responses.
FDA-approved indication: Dasatinib manufactured by Bristol-Myers Squibb and marketed as Sprycel, is a second-generation, oral, small molecule multitargeted inhibitor. Sprycel, specifically is a kinase inhibitor recommended for the treatment of: ● Adult patients who are newly diagnosed with the Ph+ (Philadelphia chromosome-positive) CML in the chronic phase. ● Adult patients who are carrying accelerated, chronic, myeloid or the lymphoid blast phase Ph+ CML with the resistance or with the intolerance before the therapy including imatinib. ● Adult patients with the Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) with resistance or intolerance before therapy. ● Pediatric patients 12 month of age and older with the Ph+ CML in the chronic phase. ● Pediatric patients 12 month of age and older with the newly diagnosed Ph+ ALL together with the chemotherapy. Side Effects: The most commonly reported side effects of this drug include: ● fever ● infection ● suppression of the bone marrow ● headache ● hemorrhage (bleeding) ● pleural effusion ● dyspnea (difficulty breathing) ● diarrhea ● vomiting ● nausea (feeling sick) ● abdominal pain (belly ache) ● skin rash ● musculoskeletal pain ● tiredness ● swelling in arms and legs. There are currently 5 TKIs available for CML: ● Imatinib (Gleevec) ● Dasatinib (Sprycel) ● Nilotinib (Tasigna) ● Bosutinib (Bosulif) ● Ponatinib (Iclusig) Dosage: Dasatinib should be administered orally, with or without a meal. Dasatinib tablets should not be crushed or cut. Patients with the Chronic phase CML should take 100 mg once daily and patients with the Accelerated phase CML, myeloid or lymphoid blast phase CML, or Ph+ ALL should take 140 mg once daily. Dosage forms and strength: Dasatinib comes in the form of tablets. The existing strength of this drug are as follows: ● Dasatinib 20 mg ● Dasatinib 50 mg ● Dasatinib 70 mg ● Dasatinib 80 mg ● Dasatinib 100 mg ● Dasatinib 140 mg Is dasatinib a chemo drug? Sprycel is the innovator/trade name for the generic chemotherapy drug dasatinib 20 mg . In a few circumstances healthcare providers may recommend the trade name sprycel cml when referring to the generic Dasatinib. Is dasatinib an immunosuppressant? Dasatinib is a targeted therapy, and mainly exerts an immunosuppressive effect on the CD8+ T cells specific for the viral and leukemia antigens. It functions not just only as an anti-neoplastic in Chronic Myeloid Leukemia but can also act as an immunosuppressive agent. List of Chronic Myeloid Leukemia medication: The below mentioned list of medicines are in some how related to, or used in order to treat CML condition. ● Hydrea (hydroxyurea) ● Iclusig (ponatinib) ● Agrylin (anagrelide) ● cyclophosphamid ● Myleran (busulfan) ● Synribo (omacetaxine) ● peginterferon alfa-2b ● fludarabinefludarabine Note: In order to explore more about above mentioned any drug, please see full prescribing information. Before starting treatment with any drug, consult your doctor. Read - New Treatments of Psoriatic Arthritis Difference Between CLL and SLL Uncontrollable and continuous multiplication of cells present in the breast leads to the formation of a lump that can cause breast cancer.
How does breast cancer start? There are some cells that grow abnormally faster than normal cells and do not have the property of normal functioning cells. The main cause of breast cancer has not been discovered yet however it has been found that it is caused due to certain mutations in the DNA of breast cells leading to continents division. How long does it take breast cancer to develop? For the physical examination by a doctor or by detecting itself the breast cancer cell should divide for at least 30th cell cycle. Up to the 28th cell cycle, no one can detect the presence of cancer in the breast. Each cell cycle takes at least 1 to 2 month and cancer which is felt now has been developing from two to five years ago. What are the 5 warning signs of breast cancer? The 5 warning signs of breast cancer are mentioned as follows: ● Nipple discharges include blood. ● Lump in the breast or armpit. ● Swelling on thickening in a particular part of the breast ● Irritation of breast skin ● Redness in the breast or nearby nipple area What are the 4 types of breast cancer: The 4 major types of breast cancer include: ● Ductal carcinoma in situ ● Invasive ductal carcinoma ● Inflammatory breast cancer ● Metastatic breast cancer Other Effective medications: There are several other medications which are quite effective, mentioned as follows: Anastrozole (Arimidex): It is an anticancer hormonal therapy medication belonging to non-steroidal aromatase inhibitor class drugs. Anastrozole uses: Anastrozole 1 mg tablet medication is used for the treatment of postmenopausal breast cancer in women. Arimidex for men is basically less effective for treating gynecomastia, in contrast to the SERMs like tamoxifen. How to take anastrozole 1mg Tablet: it is available in tablet form that is taken orally with or without food. An anastrozole 1 mg usp tablet is taken at the same time each day. Buy Arimidex: This drug can be bought by any registered pharmaceutical wholesaler. In order to buy arimidex, a respective patient should hold a valid doctor's prescription. Some medications do not require a valid doctor's prescription thus it is also known as a non-prescription or over-the-counter arimidex. How to buy liquid anastrozole: This drug is available at all registered pharmaceutical companies. The online order can also be placed by visiting the company's official website. Drugs approved to treat breast cancer: Below mentioned a few drugs that are commonly approved for the treatment of breast cancer these drugs are: ● Afinitor (Everolimus) ● Aredia (Pamidronate Disodium) ● Arimidex (Anastrozole) ● Aromasin (Exemestane) ● Atezolizumab ● Capecitabine ● Cyclophosphamide ● Docetaxel ● Doxorubicin Hydrochloride ● Eribulin Mesylate ● Fareston (Toremifene) Read - All about breast cancer New Treatments of Psoriatic Arthritis What is tofacitinib used for? Tofacitinib (Xeljanz) is a type of drug known as a Janus kinase (JAK) inhibitor. In November 2012, the U.S. FDA granted an approval to tofacitinib in order to treat adult patients with the moderate to severe active rheumatoid arthritis. How tofacitinib works? It specifically functions by blocking the action of the Janus kinase enzymes, which are generally involved in the inflammation that causes the symptoms such as pain and joint swelling in rheumatoid arthritis and psoriatic arthritis. Xeljanz side effects: The most common side effects are headaches and diarrhoea. These side effects are not serious and should soon pass. Feeling sick is also fairly common, basically when you foremost started receiving tofacitinib. Some other reported adverse reactions are as follows: ● Nasopharyngitis ● Nausea ● Indigestion ● Cough ● Dizziness ● Vomiting ● Back pain ● Joint pain ● Rash ● Muscle weakness/pain ● Upper respiratory tract infection How to diagnose psoriatic arthritis? Diagnosing of psoriatic arthritis starts with the physical exam in order to look for painful and swollen joins, skin and nail changes. X-rays or scans such as ultrasound, CT or MRI can show the damage of the joint. Blood tests can help rule out some other diseases, and a skin biopsy may help in order to confirm psoriasis. What are the 5 types of psoriatic arthritis? Psoriatic arthritis is basically categorized into five types: ● Predominant distal interphalangeal joint disease. ● Asymmetrical oligoarthritis. ● Polyarthritis. ● Spondylitis. ● Arthritis mutilans. What joints are affected by psoriatic arthritis? Psoriatic arthritis can be responsible for affecting single or multiple different joints. Your toes and fingers may swell and look like sausages, known as dactylitis. Toenails and fingernails may become pitted. How long does it take for tofacitinib to work? Tofacitinib is a long-term treatment. Most people who get benefit from this drug will experience an improvement within a few weeks of initiating the treatment, but further improvements can be seen after the initial six months of the treatment. List of medications to treat psoriatic arthritis: Psoriatic arthritis treatment depend on your level of pain, swelling or stiffness. Mild arthritis flares can be treated with the nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil or Motrin) or naproxen sodium (Aleve). Corticosteroid shots can be useful and ease the pain as well as swelling in an affected joint. Apart from xeljanz 5 mg, there are some other FDA approved existing medications which can be useful, are as follows: ● Humira (adalimumab) ● Enbrel (etanercept) ● Otezla (apremilast) ● Cosentyx (secukinumab) ● Stelara (ustekinumab) ● Remicade (infliximab) ● Taltz (ixekizumab) ● Rayos (prednisone) ● Tremfya (guselkumab) ● Leflunomide ● Sulfasalazine ● Cimzia (certolizumab) ● Simponi (golimumab) ● Trexall (methotrexate) ● Clinacort (triamcinolone) ● Cimzia (certolizumab) ● Mycophenolate mofetil ● Orencia (abatacept) ● Amjevita (adalimumab) ● Cortone Acetate (cortisone) ● Inflectra (infliximab) Note: In order to know about all these products please see, full prescribing information. Prior to starting any kind of treatment, foremost consult your physician. Rheumatoid Arthritis Symptoms and Treatment Best Arthritis Medication What is the exact difference between Hodgkin lymphoma and non-Hodgkin lymphoma? Some common difference is between Hodgkin lymphoma and non-Hodgkin lymphoma are listed below:
How long is it possible to live after Hodgkin lymphoma treatment? Hodgkin lymphoma is one of the most treatable cancers with a range of almost 90% survival rate of a patient for 5 years. Patients treated with Hodgkin lymphoma show almost 90 out of 100 patients has shown a healthy and successful lifestyle for more than five years. Drugs approved for Hodgkin lymphoma: Drugs approved for the treatment of Hodgkin lymphoma are listed below: Chlorambucil
Some other FDA approved drugs used in the treatment of hot king lymphoma discussed below: Bleomycin: This drug is used in the treatment of cancers such as Hodgkin lymphoma, non-Hodgkin lymphoma, survival cancer, and testicular cancer. Bleomycin injection is injected intravenously. Procarbazine hydrochloride: This drug is used in the treatment of Hodgkin lymphoma and brain cancer. It is taken orally and combined with other medications such as prednisone, chlormethine, and vincristine in the case of Hodgkin lymphoma treatment. Brentuximab vedotin: This drug is sold under the brand name Adcetris. Adcetris FDA labeled is an approved medication used in the treatment of Hodgkin lymphoma after failure of autologous stem cell transplant (ASCT). Adcetris injections are available in a single-use vial containing 50 mg lyophilized powder. Brentuximab vedotin 50mg dose is adjusted according to moderate to severe hepatic impairment disorder. Some common side effects of adcetris 50mg include upper respiratory tract infection, anemia, nausea, diarrhea, peripheral sensory neuropathy, cough, and vomiting. Some commonly asked questions regarding Brentuximab vedotin are: How long does Brentuximab take to work? This drug effect is seen after 4 to 5 cycles of treatment however the cycle of treatment depends upon several factors such as how did treatment affect, how you respond, whether or not you should go for stem cell transplant. Does Brentuximab cure cancer? Brentuximab vedotin is a type of immunotherapy that strengthens the immunity of the body to attack against cancer cells. This drug interferes with the normal functioning of multiplication and growth of the cancerous cells. The efficiency of this drug is enhanced if it is incorporated with ibrutinib for the treatment of Hodgkin lymphoma. Contact /WhatsApp 9650877511 International Pharmaceutical Wholesalers Read - brentuximab vedotin patient information Who makes sorafenib? Sorafenib was co-developed as well as co-marketed by Bayer and Onyx Pharmaceuticals as Nexavar. Sorafenib uses: It is basically a kinase inhibitor class of drug recommended in the treatment of primary Kidney cancer, FLT3-ITD positive AML, radioactive iodine resistant advanced thyroid carcinoma, advanced primary liver cancer and advanced renal cell carcinoma. What are the signs of kidney cancer? Kidney cancer generally called renal cancer occurs in Kidneys and slowly spreads to other body parts. At the initial phase, no signs of Kidney cancer has been detected however at advancing stage the common signs and symptoms of Kidney cancer include weight loss, loss of appetite, blood in urine, lower back pain, anemia, fever, tiredness, the formation of lump on lower side back Something about liver and thyroid cancer Liver cancer: Cancer that begins in the cell of the liver is known as liver cancer. The most common type of cancer is hepatocellular carcinoma. Other types include neuroblastoma, intrahepatic cholangiocarcinoma. Some common symptoms of liver cancer include nausea, vomiting, loss of appetite, abdominal swelling, white stool, jaundice, weight loss, weakness, and fatigue. Thyroid cancer: Cancer in the thyroid gland of the human body that produces hormones responsible for maintaining blood pressure, regulating heart rate, body temperature, and weight. Several types of thyroid cancer exist in which some are slow-growing whereas some are aggressively growing. At the initial stage, there is typically no signs and symptoms of Thyroid cancer however with the advancement of Cancer some symptoms such as a lump in the neck, difficulty in swallowing, swollen lymph node in the neck, changes in the voice, pain in the neck and throat occurs Is sorafenib considered chemotherapy? It is a targeted therapy drug that works by stopping or slowing down the multiplication and growth of cancerous cells. Sorafenib can cure liver cancer if used as a first-line treatment before surgery. How does sorafenib work? Targeted therapy works by identifying the specific functioning of cancerous cells and finding its way to inhibit or block the protein synthesis, cell division, or cell growth. Sorafenib blocks cancerous cell growth in different ways. This drug targets the production of several enzymes in the cell or on the surface of the cancerous cell. These targeted enzymes are involved in angiogenesis. This therapy works as an antiangiogenesis that blocks the supply of oxygen to the tumor so that they starve to death. Sorafenib dose: Sorafenib is available in a tablet form of 200 mg concentration. Two tablets of 200mg (400mg dose) are taken daily according to the doctor's prescription. How to take sorafenib tablets: Sorafenib 200mg is consumed orally without food. The pill should be taken either before a meal or after 2 hours of a meal. Swallow the tablet as a whole. Do not crush, grind, or smash the tablet. Sorafenib side effects: The common side effect of sorafenib are mentioned below: ● Diarrhea ● Abdominal pain ● Rash ● Nausea ● Hand-foot syndrome ● Fatigue ● Weight loss ● Redness, swelling, and peeling of skin in hands and feet. ● Gastrointestinal pain ● Infection ● Hypertension ● Hemorrhage Some serious adverse reaction of sorafenib tablets are discussed below: ● Cardiovascular disorder ● Hypertension ● Bleeding ● Gastrointestinal perforation ● Embryo-fetus damage ● Drug-induced liver injury ● Dermatological toxicity Note: For full information patients must talk about prescribing information with their healthcare provider. Tollfree - +91 1800 889 1064 International Pharmaceutical Wholesalers Read - KIDNEY CANCER INTRODUCTION A VISUAL GUIDE TO BREAST CANCER |
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