What is tofacitinib used for? Tofacitinib (Xeljanz) is a type of drug known as a Janus kinase (JAK) inhibitor. In November 2012, the U.S. FDA granted an approval to tofacitinib in order to treat adult patients with the moderate to severe active rheumatoid arthritis. How tofacitinib works? It specifically functions by blocking the action of the Janus kinase enzymes, which are generally involved in the inflammation that causes the symptoms such as pain and joint swelling in rheumatoid arthritis and psoriatic arthritis. Xeljanz side effects: The most common side effects are headaches and diarrhoea. These side effects are not serious and should soon pass. Feeling sick is also fairly common, basically when you foremost started receiving tofacitinib. Some other reported adverse reactions are as follows: ● Nasopharyngitis ● Nausea ● Indigestion ● Cough ● Dizziness ● Vomiting ● Back pain ● Joint pain ● Rash ● Muscle weakness/pain ● Upper respiratory tract infection How to diagnose psoriatic arthritis? Diagnosing of psoriatic arthritis starts with the physical exam in order to look for painful and swollen joins, skin and nail changes. X-rays or scans such as ultrasound, CT or MRI can show the damage of the joint. Blood tests can help rule out some other diseases, and a skin biopsy may help in order to confirm psoriasis. What are the 5 types of psoriatic arthritis? Psoriatic arthritis is basically categorized into five types: ● Predominant distal interphalangeal joint disease. ● Asymmetrical oligoarthritis. ● Polyarthritis. ● Spondylitis. ● Arthritis mutilans. What joints are affected by psoriatic arthritis? Psoriatic arthritis can be responsible for affecting single or multiple different joints. Your toes and fingers may swell and look like sausages, known as dactylitis. Toenails and fingernails may become pitted. How long does it take for tofacitinib to work? Tofacitinib is a long-term treatment. Most people who get benefit from this drug will experience an improvement within a few weeks of initiating the treatment, but further improvements can be seen after the initial six months of the treatment. List of medications to treat psoriatic arthritis: Psoriatic arthritis treatment depend on your level of pain, swelling or stiffness. Mild arthritis flares can be treated with the nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil or Motrin) or naproxen sodium (Aleve). Corticosteroid shots can be useful and ease the pain as well as swelling in an affected joint. Apart from xeljanz 5 mg, there are some other FDA approved existing medications which can be useful, are as follows: ● Humira (adalimumab) ● Enbrel (etanercept) ● Otezla (apremilast) ● Cosentyx (secukinumab) ● Stelara (ustekinumab) ● Remicade (infliximab) ● Taltz (ixekizumab) ● Rayos (prednisone) ● Tremfya (guselkumab) ● Leflunomide ● Sulfasalazine ● Cimzia (certolizumab) ● Simponi (golimumab) ● Trexall (methotrexate) ● Clinacort (triamcinolone) ● Cimzia (certolizumab) ● Mycophenolate mofetil ● Orencia (abatacept) ● Amjevita (adalimumab) ● Cortone Acetate (cortisone) ● Inflectra (infliximab) Note: In order to know about all these products please see, full prescribing information. Prior to starting any kind of treatment, foremost consult your physician. Rheumatoid Arthritis Symptoms and Treatment Best Arthritis Medication
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