Prescribing information (PI): "For full information read PI" and consult a Physician before initiating any treatment. All about Multiple Myeloma: Multiple myeloma is a type of cancer in plasma cells of a white blood cell. This cancerous cell grows and produces abnormal antibodies that do not fight with infections. In the case of multiple myeloma, the abnormal cancer cell accumulates in the bone marrow and causes complications. To know more about multiple myeloma click on the link given below: How prognosis determined for the patient with Multiple Myeloma is: Prognosis is the estimation of a doctor to know how multiple myeloma will affect the life of the patient and how a patient will respond to the treatment. Prognosis and survival rate of the patient depend on several factors such as the stage of multiple Myeloma, type of cancer, history, response to treatment, and treatment is chosen. Prognosis in a patient is determined by a prognostic factor. This factor influences the recent treatment response. Multiple Myeloma Diagnosis: There are several Diagnostic techniques to determine if a patient is suffering from multiple myeloma or not. These techniques are listed below: • Blood and urine tests: Elevation in the protein level in patient urine and blood due to secretion of monoclonal immunoglobulin by Myeloma cells has been detected. • X-ray: X-ray is used to picture the human body using a radiation x-ray. It is mainly used to evaluate the Myeloma presence in bone. • Magnetic resonance imaging (MRI): is used to detect the presence of Myeloma cells in the pelvis and spine using a magnetic field. It is also used to measure the size of a tumor. • Bone marrow aspiration and biopsy: bone marrow aspiration removes a fluid sample with the help of medal however bone marrow biopsy removes solid tissue for the diagnosis of myeloma. • Fat pad aspirant: A small portion of the abdominal fat pad is taken with the help of a needle and examined under the microscope to detect the condition of amyloidosis. • Molecular testing of tumor: tumor or bone marrow samples are taken to identify the specific chromosomes. Multiple myeloma treatment: There are various therapy treatments which are cited below: • Chemotherapy: this technique is used to destroy cancerous cells by inhibiting its further activity of growth and division. In this technique, several drugs are combined for the therapy. Some successful drugs are etoposide, doxorubicin, cyclophosphamide, and melphalan. • Immunotherapy: it is also known as biological therapy in which drugs are used to enhance the immunity of natural defense and fight against cancer. Some immune-boosting drugs are thalidomide, thalidomide, and thalidomide. • Targeted therapy: this targets the cancer-specific protein and genes. This treatment blocks the spread and growth of a cancerous cell. Some examples of this therapy are ixazomib, carfilzomib, and bortezomib. Bortezomib multiple myeloma drug is a highly recommended medication by doctors. Bortezomib is available in a single vial containing approximately 4mg of it. Bortezomib 2mg specific drug. Besides all of these treatment methods, some major questions which are asked are, "Are there any natural medicines for the treatment of multiple myeloma?, then the answer is yes. Recent studies specified promising benefits of certain fruits and vegetables for prevention of cancer and complementary treatment. Various plants which are full of ursolic acid have been shown to be cytotoxic, that may inhibit a variety of cancerous cells. Foods with the ursolic acid include apples, basil, rosemary, cranberries. Cruciferous vegetables, including cabbage, cauliflower, broccoli and Brussels sprouts, contain the specific nutrients known as isothiocyanates that exhibit anti-myeloma properties. Pterostilbene, a kind of natural compound found mainly in the blueberries, exhibits anti-tumor activity. Curcumin, basically found in turmeric, which is full of anti-inflammatory and anti-cancer benefits. Bortezomib 2mg belongs to the proteasome inhibitor class drug that is used for the treatment of multiple Myeloma and Mantle cell lymphoma in a patient who has received at least one prior therapy. This drug is injected intravenously for about 3-5 seconds. Some common side effects of Bortezomib multiple myeloma drug are vomiting, nausea, diarrhea, thrombocytopenia, pyrexia, anemia, leukopenia, and psychiatric disorder. FAQ About bortezomib injection? This drug is a proteasome inhibitor class drug used in the treatment of patients suffering from multiple myeloma and Mantle cell lymphoma who have at least received one prior therapy. How do you give a bortezomib injection? This drug is injected intravenously. It is injected in the subcutaneous region into the abdomen or thigh. The amount of this drug depends upon several factors such as type of cancer, the health of the patient, height, the weight of the patient, the condition being treated, and other health problems. Is bortezomib a chemotherapy drug? Bortezomib is a type of chemotherapy called a targeted therapy drug. This is approved by the FDA for the treatment of mantle cell lymphoma and multiple myeloma. Bortezomib injection works by targeting and inhibiting the proteasome enzyme complex. This complex is a part of cancer cellular machinery that helps in controlling the level of proteins involved in cell survival and cell division. By inhibiting its function this drug causes cell apoptosis. What is the Bortezomib innovator? Velcade is the innovator brand of Bortezomib. On 11 August 2014, the U.S. Food and Drug Administration (FDA) approved this medication for the treatment of Multiple myeloma. List of multiple Myeloma drugs? Some of the most widely used drug for the treatment of multiple myeloma are: ● Melphalan: This drug is used for the treatment of multiple Myeloma patients suffering from ovarian cancer. It can either be consumed orally or injected intravenously. ● Vincristine (Oncovin): This drug is used in the treatment of acute lymphoblastic leukemia or acute myeloid lymphoma. ● Cyclophosphamide (Cytoxan): This drug is used for suppressing the immune system and in the treatment of breast cancer, multiple myeloma, leukemia, lymphoma, ovarian cancer, neuroblastoma, and small cell lung cancer. ● Etoposide (VP-16): this drug is used in the treatment of my Myeloma or leukemia. What is Bortezomib injection? This drug is basically used in the treatment of multiple Myeloma for Mantle cell lymphoma. It is injected intravenously. Some common side effects after injection for fever, diarrhea, nausea, tiredness, shortness of breath, numbness, low white blood cell, abdominal pain, and Rash. Using these drugs together to treat multiple myeloma Although a single drug may be used to treat multiple myeloma, it is preferable to use at least 2 or 3 different kinds of drugs in combination because the cancer responds better. For example: Lenalidomide (or pomalidomide or thalidomide) and dexamethasone Carfilzomib (or ixazomib or bortezomib), lenalidomide, and dexamethasone Bortezomib (or carfilzomib), cyclophosphamide, and dexamethasone Elotuzumab (or daratumumab), lenalidomide, and dexamethasone Bortezomib, liposomal doxorubicin, and dexamethasone Panobinostat, bortezomib, and dexamethasone Elotuzumab, bortezomib, and dexamethasone Melphalan and prednisone (MP), with or without thalidomide or bortezomib Vincristine, doxorubicin (Adriamycin), and dexamethasone (called VAD) Dexamethasone, cyclophosphamide, etoposide, and cisplatin (called DCEP) Dexamethasone, thalidomide, cisplatin, doxorubicin, cyclophosphamide, and etoposide (called DT-PACE), with or without bortezomib Read - ALL ABOUT MULTIPLE MYELOMA CHRONIC MYELOID LEUKEMIA TREATMENT Alternative Medicine for Multiple Myeloma
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